692 VENOM IMMUNOTHERAPY FOR INSECT HYPERSENSITIVITY

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Stinging insect allergy: current perspectives on venom immunotherapy

Systemic allergic reactions to insect stings affect up to 5% of the population during their lifetime, and up to 32% of beekeepers. Such reactions can be fatal, albeit very rarely, and fear of a further systemic reaction (SR) can lead to significant anxiety and quality of life impairment. A recent Cochrane systematic review confirmed that venom immunotherapy (VIT) is an effective treatment for p...

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In vitro immunomonitoring of insect venom-allergic patients on immunotherapy

Objective Sting challenge is the gold standard method to evaluate the therapeutic efficiency of allergen specific immunotherapy (ASIT) in hymenoptera venom allergic patients. Unfortunately, this method is risky, expensive and time consuming. Therefore, the development of an in vitro method is desirable. Recently the basophil activation test (BAT) performed with natural venom has been shown to b...

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Clinical Effectiveness of Hymenoptera Venom Immunotherapy: A Prospective Observational Multicenter Study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity

BACKGROUND Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. OBJECTIVE Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during the maintenance phase. METHODS In this observational prospective multicenter study, we followed 357 patients with estab...

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Allergen immunotherapy for insect venom allergy: protocol for a systematic review

BACKGROUND The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy. METHODS We will undertake a systematic review, which will invo...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1978

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197804001-00697